ea0049ep692 | Obesity | ECE2017
Heikela Hanna
, Adam Marion
, Portius Dorothea
, Maki-Jouppila Jenni
, Mehmood Arfa
, Adhikari Prem
, Esposito Irene
, Elo Laura
, Zhang Fu-Ping
, Ruohonen Suvi T
, Strauss Leena
, Foti Michelangelo
, Poutanen Matti
: Hydroxysteroid (17beta) dehydrogenases (HSD17Bs) form a group of enzymes that are characterized by their sequence similarity at the active site, and their ability to catalyze the conversion between the weak 17keto- and the highly active 17beta-hydroxysteroids. To study the physiological role of HSD17B13, a lipid droplet associated protein, we characterized the phenotype of knockout (KO) mice deficient in HSD17B13 (HSD17B13KO). The data revealed normal serum sex steroid conce...